Fulminant cerebral demyelination in neuromyelitis optica

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منابع مشابه

Fulminant cerebral demyelination in neuromyelitis optica.

A 43-year-old woman with a 2-year history of neuromyelitis optica (NMO; typical imaging [figure 1] and NMO–immunoglobulin G [IgG] antibody), previously treated with plasmapheresis and steroids, presented somnolent. Admission neuroimaging showed fulminant cerebral demyelination (figure 2, A and B), and she rapidly progressed to herniation (figure 2, C and D) and brain death despite 2 courses of ...

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Fulminant neuromyelitis optica in a Finnish woman – a case report

Neuromyelitis optica is a rare inflammatory, demyelinating disease of the central nervous system that predominantly targets the optic nerves and spinal cord. Our case represents an unusual and severe course of neuromyelitis optica. Despite several forms of treatment, our patient died after a severe and short-term attack.

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Neuromyelitis Optica in Children: A Rare Entity

     Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

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Neuromyelitis Optica

An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...

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Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate

BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...

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ژورنال

عنوان ژورنال: Neurology

سال: 2011

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0b013e3182242d6e